autism autism spectrum disorders
Conditions
Interventions
The intervention will consist of 24 DMP sessions, conducted in a reversal
design in which blocks of attuned movement will be alternated by non-specific
movement intervention
Sponsors
Orbis Medisch Centrum
Eligibility
Age
12 Years to 17 Years
Inclusion criteria
Inclusion criteria: adolescents age 12-16, diagnosed with Autism spectrum disorder/ASD according to DSM IV-TR, IQ (WISC) > 75
Exclusion criteria
Exclusion criteria: co-morbidity other psychopathology, e.g. ADHD; IQ (WISC)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We expect that the movement observations will show increasing signals of inter-personal engagement in participants, an increase in the overt nonverbal interaction behavior and that neuronal regulation improves. As a consequence the child*s capacities to maintain contact/relationship through intentionally attuning to another person*s movement are increased, consolidated for use over their lifetime. The main study parameters are the changes that occur between the measurements before start of the intervention (baseline) and after the intervention ended (endpoint) in the differences in: a) number of social-orienting movements of the participant (e.g. eye-contact) b) social behaviour profile drawn from parental questionnaires c) neuronal activation profile drawn from fMRI scan. d) brain anatomy drawn from the anatomical MRI scan and, indirectly, from the resting state data. | — |
Secondary
| Measure | Time frame |
|---|---|
| Throughout intervention, data from movement patterns showing engagement (e.g. eye contact) will be collected via videotapes of sessions Secondary parameters are: a) the difference in neuronal activation profile between patients and controls at endpoint b) the change in number of events of social orienting movements within subjects throughout repeated measurements during sessions 1, 6, 12, 18, 24. | — |
Countries
Netherlands
Outcome results
None listed