Brown Adipose Tissue Activity in Caucasians and South Asians

Brown Adipose Tissue Activity in Caucasians and South Asians - Brown adipose tissue and ethnicity

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36373

Enrollment

Registered

2011-08-30

Start date

2011-01-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Male European or South Asian origin Subjects should be able and willing to give informed consent 18-35 years old BMI range of 20-25 kg/m2

Exclusion criteria

Exclusion criteria: Renal failure (kreatinine>135mmol/l) Use of prescription medication

Design outcomes

Primary

Measure	Time frame
Difference in Standardised Uptake Value (SUV) of the tracer 18F-fluorodeoxyglucose (FDG) visualised with PET-CT in BAT (Caucasians vs South Asians)	—

Secondary

Measure	Time frame
-Difference in SUV of the tracer I-123 metaiodobenzylguanidine (MIBG) in BAT (Caucasians vs South Asians) -Correlation between SUV of the tracer MIBG and SUV of the tracer FDG (both in the total group and Caucasians vs South Asians) -Correlation between insulin sensitivity (as measured by euglycemic insulin clamp) and SUV of the tracer FDG.	—

Countries

Netherlands

Outcome results