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Genetic Susceptibility to Papilloma-induced Voice Disturbance

Genetic Susceptibility to Papilloma-induced Voice Disturbance - Gen-RRP

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON36369
Enrollment
60
Registered
2011-04-21
Start date
2011-08-18
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

RRP warty recurrent disease in the larynx

Interventions

None listed

Sponsors

Center for Genomic Sciences/ Allegheny General Hospital
Lead Sponsor

Eligibility

Age
2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patient must have been diagnosed with Recurrent Respiratory Papillomatosis(RRP) by an otolaryngologist. Biological mother and father of such patients: If either mother or father of such patients are not available then full siblings will be invited to participate.

Exclusion criteria

Exclusion criteria: None in the Satellite Design

Design outcomes

Primary

MeasureTime frame
Most genes contain multiple single nucleotide polymorphisms (SNP) that allow one to differentiate different alleles by their characteristic SNP pattern. Software will be used to automate the process of identifying the genotype of each affected individual and to compare it to that of his/her parents and to that of unrelated controls.

Secondary

MeasureTime frame
-

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)