Measurement of biochemical markers of bone turnover in patients with bilateral sagittal split osteotomy

Measurement of biochemical markers of bone turnover in patients with bilateral sagittal split osteotomy - Measurement of biochemical markers of bone turnover in patients with BSSO

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36318

Enrollment

Registered

2012-01-31

Start date

2011-04-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bone specific markers in urine and serum

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients for Bilateral Sagittal split Osteotomy Over 18 years old

Exclusion criteria

Exclusion criteria: Renal and liver function problems Active treatment with growth hormone Patients with Hormone replacement therapy Breastfeeding Pregnancy The use of anti-epileptics Astma patients that use inhalation steroids The use of anticoagulentia

Design outcomes

Primary

Measure	Time frame
Primary Objective: - Are there mesurable changes in biochemical markers after BSSO in serum(CTX, P1NP, BALP, Osteocalcine, Calcium, vit D. CRP, BSE, leucocyten, IL6, creatine) and in urine(hydroxylysylpyridinoline en lysyspyridinoline)? - Can serum and urine biochemical markers predict bone remodeling?	—

Secondary

Measure	Time frame
None	—

Countries

Netherlands

Outcome results