Effectiveness and cost effectiveness of a Cognitive Behavioral Therapy (CBT) program in clinically depressed adolescents; individual CBT versus care as usual.

Effectiveness and cost effectiveness of a Cognitive Behavioral Therapy (CBT) program in clinically depressed adolescents; individual CBT versus care as usual. - SAD, Study Adolescent Depression

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON36268

Enrollment

140

Registered

2011-06-15

Start date

2011-12-20

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression Depressive Disorders

Interventions

Adolescents are randomly assigned to the CBT program the *D(o)epressie cursus* or care as usual (without CBT). Adolescents assigned to the experimental condition, the D(o)epressie cursus, will rece

psycho-education (information about depression and the rationale for the aetiology of the complaints and the treatment of them), setting attainable goals (translate large goals into realistic short

Eligibility

Age

12 Years to 99 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria are: (1) age 12 until 21 years, (2) a primary diagnoses of depression (regardless the severity: mild, moderate or severe), and (3) referred to a participating mental health institution.

Exclusion criteria

Exclusion criteria: The criteria for exclusion are: (1) acute suïcide risk, (2) drug abuse (as primary diagnosis), (3) pervasive developmental disorder (as primary diagnosis), (4) bipolar disorder (as primary diagnosis), (5) day care or admission to the clinical setting and (6) not fluent in Dutch, Turkish, Arabic or Berber language.

Design outcomes

Primary

Measure	Time frame
The primary outcome measure is the presence of the depression diagnosis (present or absent) measured by means of a diagnostic interview the K-SADS. Both the adolescent, the parent and the clinician view will be taken into account. Cost effectiveness Cost diaries will be assessed to monitor costs and cost-effectiveness. These cost diaries have been used in an earlier study on anxiety (Bodden, Dirksen & Bögels, 2008) and will be complemented by parts of the TiC-P and the PRODISQ. The QALY will be calculated by means of the EuroQol.	—

Measure

Time frame

The primary outcome measure is the presence of the depression diagnosis (present or absent) measured by means of a diagnostic interview the K-SADS. Both the adolescent, the parent and the clinician view will be taken into account. Cost effectiveness Cost diaries will be assessed to monitor costs and cost-effectiveness. These cost diaries have been used in an earlier study on anxiety (Bodden, Dirksen & Bögels, 2008) and will be complemented by parts of the TiC-P and the PRODISQ. The QALY will be calculated by means of the EuroQol.

—

Secondary

Measure	Time frame
Secondary outcome measures are: 1. degree of depressive symptoms (CDI, adolescent and parent version) 2. severity of the depression (K-SADS, adolescent, parent and therapist view) 3. suicide risk taxation 4. comorbidity/psychopathology (YSR and CBCL, adolescent and parent version) 5. quality of life (EuroQol, adolescent and parent version) 6. life events (including drug abuse, maltreatment and suicide attempts) 7. depression parents (BDI) 8. psychopathology parents (ASR) 9. parenting (scales from the NOV, APQ, PDI, VTH en PDI) 10. Attachment (PARA) Moderators Moderators that will be investigated are demographic characteristics such as gender, age, ethnicity, education level and family income. Besides, comorbidity (YSR and CBCL), severity of the depression (K-SADS), psychopathology of parents (ASR) and depression in parents (BDI) will be taken into account as moderators. Mediators The following mediators will be studied in this research; negative automatic thoughts (CATS), cognitive emotion regulation (CERQ) and attribution style (CASQ). Non-specific treatment variabeles Non-specific treatment variables that will be investigated are; client expectancy of treatment, treatment adherence, satisfaction with treatment, cooperation with treatment, relationship with therapist, treatment integrity.	—

Measure

Time frame

Secondary outcome measures are: 1. degree of depressive symptoms (CDI, adolescent and parent version) 2. severity of the depression (K-SADS, adolescent, parent and therapist view) 3. suicide risk taxation 4. comorbidity/psychopathology (YSR and CBCL, adolescent and parent version) 5. quality of life (EuroQol, adolescent and parent version) 6. life events (including drug abuse, maltreatment and suicide attempts) 7. depression parents (BDI) 8. psychopathology parents (ASR) 9. parenting (scales from the NOV, APQ, PDI, VTH en PDI) 10. Attachment (PARA) Moderators Moderators that will be investigated are demographic characteristics such as gender, age, ethnicity, education level and family income. Besides, comorbidity (YSR and CBCL), severity of the depression (K-SADS), psychopathology of parents (ASR) and depression in parents (BDI) will be taken into account as moderators. Mediators The following mediators will be studied in this research; negative automatic thoughts (CATS), cognitive emotion regulation (CERQ) and attribution style (CASQ). Non-specific treatment variabeles Non-specific treatment variables that will be investigated are; client expectancy of treatment, treatment adherence, satisfaction with treatment, cooperation with treatment, relationship with therapist, treatment integrity.

—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)