Probiotic functionality of several probiotic supplements during gastro-intestinal transit in vivo in healthy human subjects

Probiotic functionality of several probiotic supplements during gastro-intestinal transit in vivo in healthy human subjects - Home-sweet-home project

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON36265

Enrollment

Registered

2011-01-24

Start date

2009-12-05

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome obesity

Interventions

placement of a naso-duodenal catheter and hereafter consumption of two oral probiotic preparations at two different occasions

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: sex: male age: 18-40 years body mass index 18-30kg/m2

Exclusion criteria

Exclusion criteria: • History of severe cardiovascular, respiratory, urogenital, gastrointestinal/ hepatic, hematological/immunologic, HEENT (head, ears, eyes, nose, throat), dermatological/connective tissue, musculoskeletal, metabolic/nutritional, endocrine, neurological/psychiatric diseases, allergy, major surgery which might limit participation in or completion of the study protocol

Design outcomes

Primary

Measure	Time frame
Sugar conversion. This by measuring: • Fructo- and Gluco-oligosaccharides • Mannitol • Sucrose • Fructose • Glucose	—

Secondary

Measure	Time frame
• Phenol red (marker for gastric emptying) • pH • Number of viable bacteria	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)