The influence of oral contraception on the 1 mg overnight dexamethasone suppression test

The influence of oral contraception on the 1 mg overnight dexamethasone suppression test - OAC-DEX

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON36254

Enrollment

Registered

2011-04-04

Start date

2011-11-15

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cushing's syndrome hypercorticism

Interventions

Performing the 1 mg Overnight Dexamethasone suppression test at the end of the third week of oral contraception. Afterwards the use of oral contraception is ceased and is the 1 mg Overnight Dexameth

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: use of oral contraception

Exclusion criteria

Exclusion criteria: Cushing's syndrome, psychiatric diseases, alcohol use of more than 7 units/week, pregnancy, steroid medication

Design outcomes

Primary

Measure	Time frame
Serum cortisol after the 1 mg overnight dexamethasone suppression test during use of OAC and after one and six weeks of ceasing of contraception. Urinary and salivary cortisol during use of OAC and after one and six weeks of ceasing of contraception.	—

Secondary

Measure	Time frame
If necessary: CBG, ACTH, free cortisol, FSH, LH	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)