The effect of chemotherapeutic agents and mechanical tongue cleaning on morning bad breath

The effect of chemotherapeutic agents and mechanical tongue cleaning on morning bad breath - Effect of chemotherapeutic agents and mechanical tongue cleaning on MBB

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON36247

Enrollment

Registered

2011-11-18

Start date

2012-01-10

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Slechte ochtend adem Morning Bad Breath (MBB)

Interventions

The control group: use fluoride toothpaste Everclean ® HEMA, which is available on the market. Intervention (test) group: use Meridol ® Halitosis: toothbrush, toothpaste, mouthwash and tongue clean

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * * 18 years - 35 years * minimum of 20 natural teeth * Non-smokers * Organoleptic mean score of minimum 2

Exclusion criteria

Exclusion criteria: * Open active caries * absence of probing depth * 5mm probing and attachment loss * 2 mm * the absence of pregnancy- breastfeeding and systemic diseases * On medications which can cause malodour * the absence of antibiotic in the last 2 months * participation in a clinical study within the previous 30 days * Ongoing dental treatment or any other medical treatment of the oral cavity

Design outcomes

Primary

Measure	Time frame
The primary outcome is moring Bad Breath and will be measured by three different methods Organoleptic score: The judge is using an arbitrary 0-5 scale (Rosenberg et al. 1991a, Rosenberg et al. 1991b further modiefied by Greenman et al. 2004). The 0 represented absence of odour, 1 was given for barely noticeable odour, 2 for slight odour, 3 for moderate odour, 4 for strong odour and 5 for extremely strong odour. Halimeter: We are using a portable industrial sulphide monitor (Halimeters, Interscan Corp., Chatsworth, CA, USA). The unit is zeroed to ambient air before each measurement, using the technique established by Rosenberg et al. (1991a, b). OralChroma assessments: A portable gas chromatography (OralChroma®) using a flame photometric detector is the preferable method if precise measurements of specific gases are required. This technology is specifically designed to digitally measure molecular levels of the three major VSC (H2S, CH3SH, and dimethyl sulfide CH3SCH3).	—

Measure

Time frame

The primary outcome is moring Bad Breath and will be measured by three different methods Organoleptic score: The judge is using an arbitrary 0-5 scale (Rosenberg et al. 1991a, Rosenberg et al. 1991b further modiefied by Greenman et al. 2004). The 0 represented absence of odour, 1 was given for barely noticeable odour, 2 for slight odour, 3 for moderate odour, 4 for strong odour and 5 for extremely strong odour. Halimeter: We are using a portable industrial sulphide monitor (Halimeters, Interscan Corp., Chatsworth, CA, USA). The unit is zeroed to ambient air before each measurement, using the technique established by Rosenberg et al. (1991a, b). OralChroma assessments: A portable gas chromatography (OralChroma®) using a flame photometric detector is the preferable method if precise measurements of specific gases are required. This technology is specifically designed to digitally measure molecular levels of the three major VSC (H2S, CH3SH, and dimethyl sulfide CH3SCH3).

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Secondary

Measure	Time frame
Tongue coating index: The procedure to assess coating is a modification of the method as described by Miyazaki et al. (1995) and described in detail by Mantilla Gomez et al. (2001). Enquete: subjects give their opinions about their experience of this clinical trial	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)