minimal invasive surgery pneumoperitoneum
Conditions
Interventions
None listed
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Age
Exclusion criteria
Exclusion criteria: Diagnosis of necrotizing enterocolitis, because of prior elevated iFABP Emergency surgery Inflammatory bowel disease, or other bowel disorders, which can cause iFABP elevations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peroperative measurements of: • Urinary iFABP: as a measurement of the ischemia in the intestines (Detection limit 40pg/ml pg/ml). Urinary samples are taken each 10 minutes during the pneumoperitoneum, because of the half time of 11 minutes for iFABP. A control sample is taken before the start of the pneumoperitoneum and the last sample is taken 10 minutes after surgery. • Urinary Creatinin: to calculate iFABP/ creatinin ratio (cut off point 2.2 pg/nmol). In the same samples as iFABP • Intra-abdominal pressure and insufflation flow on monitor are registered in the same 10 minutes interval as the urine samples | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-operative measurement of: • Urinary iFABP: Urinary samples by active urination of the patient, after the removal of the urinary catheter (the time is noted), until 24h after the surgery. • Urinary Creatinin: In the same samples as iFABP • Restoration of Gastro-intestinal function (per 6h in the first 24h; daily in the first week) (First defecation, first oral feeding, and full oral feeding) • Hospital stay in days | — |
Countries
Netherlands
Outcome results
None listed