obstructive sleep apnea syndrome (OSAS)
Conditions
Interventions
Stroke patients who screen positive for OSAS will be randomized over four weeks
of nocturnal use of CPAP and four weeks of CAP treatment dealy (N=70). These
patient groups will be compared at baseli
case-control part of the project).
Sponsors
Heliomare
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: First-time stroke confirmed by neurological assessment and CT-scan or MRI-scan Baseline measurement (T
Exclusion criteria
Exclusion criteria: Severe unstable medical conditions Severe cardiac problems (like angina pectoris or pacemaker/ventricular impairments) Severe pulmonal disease (severe dyspnea of effort or severe pulmonal emphysema) Severe aphasia or confusion, which could strongly influence the performance on the neuropsychological assessment Severe psychiatric or somatic comorbidity, which could strongly influence the performance on the neuropsychological assessment Central SAS only Severe OSAS (AHI>60 in combination with desaturations below 70%), which could endanger patient's health if CPAP treatment is not immediately started Obesity hypoventilation syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study parameters are cognitive and functional outcome. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary measures are fatigue, mood and sleep quality. Sociodemographic and clinical data, CPAP compliance, nocturnal arousal and rehabilitation therapy will be included as control measures. | — |
Countries
Netherlands
Outcome results
None listed