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PTSD in children: underlying mechanisms and treatment

PTSD in children: underlying mechanisms and treatment - PTSD in children

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON36199
Enrollment
120
Registered
2011-11-14
Start date
2011-10-01
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-traumatic stress disorder stress complaints

Interventions

Participants with PTSD will randomly be assigned to one of the following to treatments as part of the study by Diehle (MEC 09/076). For both treatment conditions 8 sessions of 60 minutes will be imp
Relaxation
Affective modulation
Cognitive coping and processing
Trauma narrative
In vivo mastery of trauma reminders
Conjoint child-parent sessions
Enhancing future safety and development. EMDR: The following components are included in the protocols: psychoeducation and preparation
assessment
installation
positive closure and enhancing future safety.

Sponsors

Academisch Medisch Centrum
Lead Sponsor

Eligibility

Age
2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Involvement in at least one traumatic event Age 8 through 17 years

Exclusion criteria

Exclusion criteria: - Acute suicidal - Mental disorders due to a general medical condition - Meeting the criteria of one of the following DSM IV TR-diagnosis: psychotic disorder, substance use disorder, pervasive develop disorder (e.g. autism), mental retardation - Known presence of a significant medical illness including cardiac arrhythmias and epilepsia - Pregnancy - Gross obesity (weight greater than 150% of ideal body weight) or growth failure (height under 3rd percentile) - The use or presence of medication with central nervous system or HPA axis effects within the 2 weeks before measures - Claustrophobia - Presence of any metal or electrical conductive implants or foreign bodies

Design outcomes

Primary

MeasureTime frame
Neuroimaging: (f)MRI, DTI, Physiological measures: Heartrate(variability), Skin conductance Endocrinological measures: Cortisolconcentration in saliva

Secondary

MeasureTime frame
CAPS-CA (interview to help diagnose PTSD) ADIS (interview to screen for anxiety disorders) cPTCI, RCADS, CRIES, SDQ, Kidscreen

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)