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Stress reactivity in the context of infant signals

Stress reactivity in the context of infant signals - Stress reactivity in the context of infant signals

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON36194
Enrollment
50
Registered
2011-07-05
Start date
2011-09-15
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

risk for child abuse risk for child abuse

Interventions

Oxytocin or placebo administration: half of the participants will receive oxytocin or placebo

Sponsors

Universiteit Leiden
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: woman, 18-30 years old, without children

Exclusion criteria

Exclusion criteria: Potential participants for the fMRI session will be prescreened for contra-indications for fMRI, which include metal implants, heart arrhythmia, claustrophobia, and possible pregnancy. They will additionally be prescreened for head trauma, drug or alcohol abuse and psychiatric disorder. Women younger than 18 years old and older than 30 years old and men are excluded.

Design outcomes

Primary

MeasureTime frame
fMRI: we expect changes in brain activation in region involved in emotion regulation during exposure to infant crying compared to control sounds. We also expect a change in activation in these regions when participants are presented with pictures of adults and infant with emotional face expressions, compared to a control task. In addition, we expect oxytocin effects on brain activation during these empathy tasks and during infant crying.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)