The incidence of late-onset Pompe disease in subjects with obstructive sleep apnea

The incidence of late-onset Pompe disease in subjects with obstructive sleep apnea - Pios

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36188

Enrollment

500

Registered

2011-09-19

Start date

2012-02-09

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rare muscle disorder sleep disorder

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: a.age over 18 years b.a diagnosis of OSAS no older than 5 years c. Diagnosis of OSAS confirmed by polysomnography with a apneu-hypopneu index higher than 15

Exclusion criteria

Exclusion criteria: a.severe left-sided heart failure b.active psychiater-diagnosed mental disorder, thereby not able to provide informed consent c.clinical suspicion on vascular cerebral accident located in the ventral medulla of the brain stem.

Design outcomes

Primary

Measure	Time frame
deficiency of the lysosomal enzyme acid -glucosidase	—

Secondary

Measure	Time frame
none	—

Countries

Netherlands

Outcome results