What is the distribution of desmosine in serum in healthy subjects and patients with lung disease?

What is the distribution of desmosine in serum in healthy subjects and patients with lung disease? - Distribution of serum desmosine

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36180

Enrollment

200

Registered

2012-03-06

Start date

2012-08-15

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic bronchitis COPD

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Control population: adult, mentally competent subjects without pulmonary disease COPD population: adult, mentally competent patients. (The diagnosis was made **according to GOLD guidelines. ).

Exclusion criteria

Exclusion criteria: Control population; pregnancy, pulmonary complaints COPD population; reversibility in lung function (> 12% and 200ml), recent COPD exacerbation (

Design outcomes

Primary

Measure	Time frame
- Normal serum desmosine (DES) ug / L for healthy subjects and patients with COPD - Inter-day variation DES - Correlatie with 24-hour urine DES/ serum DES	—

Secondary

Measure	Time frame
Difference between healthy smokers and healthy non-smokers Subgroup analysis GOLD I-IV COPD	—

Countries

Netherlands

Outcome results