thrombocytopenia
Conditions
Interventions
Randomization of patients between platelet transfusion support with standard
plasma aphaeresis platelet concentrate: 10 * 10 9 platelets/kg body weight in a
volume of 10 mL/kg body weight (Arm A), o
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: - Neonates,
Exclusion criteria
Exclusion criteria: - Neonatal allo-immune thrombocytopenia (NIATP) - Maternal ITP - Therapeutic platelet transfusion during surgery - Platelet transfusion during red blood cell exchange. - Platelet transfusion during extracorporal membrane oxygenation (ECMO).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess recovery, estimated by platelet transfusion increment at 1 hour and 24 hour. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To assess the safety (bleeding / thrombotic complications / adverse transfusion reactions). 2. To assess the transfusion interval, estimated as interval to next transfusion. 3. To assess the donor exposure. | — |
Countries
Netherlands
Outcome results
None listed