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Investigating the link between taste perception and circulating levels of of insulin (and related metabolic hormones): a pilot study.

Investigating the link between taste perception and circulating levels of of insulin (and related metabolic hormones): a pilot study. - TPMH (Taste Perception and Metabolic Hormones)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON36154
Enrollment
40
Registered
2011-05-19
Start date
2011-11-22
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

taste and hormonal regulation Taste-induced regulation of metabolic hormones

Interventions

None listed

Sponsors

Onze Lieve Vrouwe Gasthuis
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy subjects: male, caucasian, age 30-55, Body Mass Index between 18.5 and 24.9, that are tasters (n=15) and non-tasters (n = 15) male diabetic subjects type 2 age 30-55, bmi> 18.5 (n=10)

Exclusion criteria

Exclusion criteria: Healthy subjects : Age below 30 years or over 55 years, Body mass index lower than 18.5 kg/m2 or higher than 24.9 kg/m2, Psychiatric morbidity (eating disorder, depression, alcoholism), Co-morbidity, (cardiovascular disease, thyroid disease, diabetes), Previous history of cancer, Use of regular anti-inflammatory medication, Consumption of diets or supplements high in phytoestrogens, Smoking Diabetics: use of GLP-1 agonists; BMI

Design outcomes

Primary

MeasureTime frame
- Fasting plasma and saliva levels of circulating hormones (Ghrelin, Leptin, Insulin, GIP, GLP-1, PP, PYY, BDNF, NPY, Adiponectin) - Picture of the tongue to count the number of taste buds per cm2 - Taste perception assessment with PTC strips - A copy of the handpalm and fingers of the right hand, which will enable the analysis of the potential influence of prenatal hormones by calculating the ratio between the index and the ring finger

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)