taste and hormonal regulation Taste-induced regulation of metabolic hormones
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy subjects: male, caucasian, age 30-55, Body Mass Index between 18.5 and 24.9, that are tasters (n=15) and non-tasters (n = 15) male diabetic subjects type 2 age 30-55, bmi> 18.5 (n=10)
Exclusion criteria
Exclusion criteria: Healthy subjects : Age below 30 years or over 55 years, Body mass index lower than 18.5 kg/m2 or higher than 24.9 kg/m2, Psychiatric morbidity (eating disorder, depression, alcoholism), Co-morbidity, (cardiovascular disease, thyroid disease, diabetes), Previous history of cancer, Use of regular anti-inflammatory medication, Consumption of diets or supplements high in phytoestrogens, Smoking Diabetics: use of GLP-1 agonists; BMI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Fasting plasma and saliva levels of circulating hormones (Ghrelin, Leptin, Insulin, GIP, GLP-1, PP, PYY, BDNF, NPY, Adiponectin) - Picture of the tongue to count the number of taste buds per cm2 - Taste perception assessment with PTC strips - A copy of the handpalm and fingers of the right hand, which will enable the analysis of the potential influence of prenatal hormones by calculating the ratio between the index and the ring finger | — |
Countries
Netherlands