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The short-term effect of glucose and sacharose ingestion on cognitive performance and mood in elderly subjects

The short-term effect of glucose and sacharose ingestion on cognitive performance and mood in elderly subjects - Sweet Thoughts

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON36126
Enrollment
42
Registered
2011-08-16
Start date
2011-09-01
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cognitive performance mental health

Interventions

Three different test drinks will be consumed at three different time moments
a glucose drink (50 g), a sacharose drink (100 g) and a saccharine drink (23,7 mg) serving as the placebo. All drinks contain 240 ml of water and will have the same taste and appearence by adding 1

Sponsors

De Suikerstichting Nederland
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Elderly women and men >= 70 years Memory complaints Able to understand and perform study procedure

Exclusion criteria

Exclusion criteria: • Type I or type II diabetes (fasted blood glucose level >= 7,0 mmol) • Parkinson disease • MMSE 16 (to exclude depressive subjects) • Pharmacological antidepressiva or medication for dementia • Liver disease

Design outcomes

Primary

MeasureTime frame
The primary outcome will be the difference in memory after the glucose drink and the sacharose drink versus the placebo drink. Different sensitive memory tests will be used.

Secondary

MeasureTime frame
Next to the effect of glucose and sacharose on memory, the effect on attention will be measured by performing a high-demanding attention task. Furthermore, mood will be assessed by the POMS-questionnaire. Blood glucose response will be determined, even as blood levels of insulin.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)