blood poisoning sepsis
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Age > 18 years - Presence of an arterial line - Patients who score positive for sepsis according to the Bone criteria (at least 2 SIRS criteria plus clinical suspicion of infection).
Exclusion criteria
Exclusion criteria: - No informed consent. - Patients receiving > 24 hours of antibiotic treatment for a suspected infection prior to ICU admission. - Previous participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality is the primary study endpoint. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints include pathogen etiology, systemic inflammatory parameters and MODS. The secondary endpoints will enable us to develop a predictive model for risk stratification for sepsis and provides insight in the pathophysiologic processes of sepsis and might lead to novel therapeutic interventions. | — |
Countries
Netherlands
Outcome results
None listed