postoperative pain
Conditions
Interventions
Controlgroup: standard care: Peroperative placebo infiltration, postoperative
Patient Controlled Analgesia (PCA) with morfine during 20 hours.
Interventiongroup: peroperative peri- en intraarticular
Sponsors
Meander Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age > 18 years Total knee arthroplastia of one knee Short track program
Exclusion criteria
Exclusion criteria: revision of former total knee arthroplastia, chronic use of opioids, use of steroids, bilateral surgery, contra-indication for spinal or epidural analgesia, ASA-score > 3, time of surgery > 2 hours, intolerance of study medication, epilepsia, sensibility disorder of the leg, former patellectomy, (acute of chronic) infection of the knee, psychiatric illness, neuromuscular effects, language barrier, immunologic disease, BMI > 40, alcohol abusus, pregnant women,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS-score 6 hours after operation | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain management: need for opiates in the first 24 hours, incidence of severe pain (NRS >7) in the first 24 hours, VAS-score whilest leaving recovery, the evening after surgery and the first 4 days measured 3 times a day. Side effects: incidence and severity of nausea and vometing Recovery: MILAS assistance scale, flexion of knee, hospital stay | — |
Countries
Netherlands
Outcome results
None listed