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MRI study of dynamic isolated lumbar extensor resistance training effect on multifidus muscle cross sectional area and fat infiltrations in patients with non-specific low back pain - a pilot study.

MRI study of dynamic isolated lumbar extensor resistance training effect on multifidus muscle cross sectional area and fat infiltrations in patients with non-specific low back pain - a pilot study. - Multifidus-studie

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON36072
Enrollment
20
Registered
2011-05-16
Start date
2011-05-18
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aspecifieke lagerugpijn chronic low back pain lumbago

Interventions

The participants will undergo once a week an isolated dynamic resistance training during ten weeks, in which the lumbal multifidus muscle will be trained. They will undergo no other back muscle ther

Sponsors

Sint Antonius Ziekenhuis
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Sex: man - Age: 30 years or older - Symptoms: non-specific low back pain since 12 week or longer .

Exclusion criteria

Exclusion criteria: - Sex: woman - Age: younger than 30 years - History of surgical lumbal intervention, myopathy, muscledystrophia, spinal deformaty, idiopathic scoliosis, vertebral fractures, congenital malformations, severe hernia in need of a surgical intervention, spondylolysis, osteoporosis, vertebral metastasis and morbus Bechterew. Physical effort leads to extra exclusion criteria: angina pectoris, untreatable hypertension, untreatable diabetes mellitus, epilepsia, active rheumatic disease, severe neurologic degenerative diseases like multiple sclerosis and severe coagulation disorders. - MRI contra-indications: claustrophobia, metal in the body (e.g. pacemaker, splinter in the eye).

Design outcomes

Primary

MeasureTime frame
The lumbal multifidus muscle may be imaged by ultrasound, CT and MRI. Ultrasound is only suitable for superficial muscles and the resolution is low, which will lead to inferior tissue discrimination. CT and MRI have a highter resolution and therefore good tissue discrimination. Given the radiation exposure of CT, MRI is the most appriorate method for this study. The measurements will be performed by manually drawing the circumference of the muscle. Software will calculate the cross sectional area. Fat infiltration will be divided according to standard criteria: - Normal/mild (fat infiltration 10% and 50% of the cross sectional area) The functional cross-sectional area (FCSA) of the muscle will be calculated to quantify the condition of the muscle. The FCSA is the cross sectional area of the muscle isolated from fat.

Secondary

MeasureTime frame
To quantify the level of functional (ADL) limitations caused by low back pain, all participants will fill in validated questionaire at the time they undergo the MRI scans: the Roland-Morris Disability Questionnaire (RDQ) and the Patiënt Specifieke Klachten (PSK). Fysiotherapie MTG uses these questionaire for all patients.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)