The physiological role of bile acidmediated glucagonlike peptide*1 release in humans: the Cerebrotendinous Xanthomatosis Mixed Meal Test study

The physiological role of bile acid*mediated glucagon*like peptide*1 release in humans: the Cerebrotendinous Xanthomatosis Mixed Meal Test study - -

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36008

Enrollment

Registered

2012-02-01

Start date

2013-05-03

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bile acid synthesis defect

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: *Adult age (older than 18 years of age) *Body mass index 19*30 kg/m2 *General good health (normal liver and renal function) *HbA1c below 7% *Ability to give informed consent

Exclusion criteria

Exclusion criteria: Since CTX is a rare disorder, little exclusion criteria exist. However, patients that use medication that interferes with glucose metabolism such as oral antidiabetic medication or insulin are not included.

Design outcomes

Primary

Measure	Time frame
Plasma bile acids, GLP-1, glucose	—

Secondary

Measure	Time frame
free fatty acidsn,thyroid hormones, resting energy expenditure	—

Countries

Netherlands

Outcome results