Uridine bloedbeeld na uridine monofosfaat inname Uridine bioavailability uridine blood levels
Conditions
Interventions
All subjects will undergo a single intake of 125ml of the allocated study
product during the study visit, and have blood sampled to determine uridine
levels.
Sponsors
Danone Research - Centre for Specialised Nutrition
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: -Male -Age 50-70 years, inclusive -BMI 18- 28kg/m2, inclusive -Written informed consent
Exclusion criteria
Exclusion criteria: -Any condition that may interfere with the definition *healthy volunteer* according to the investigator, with special attention to the presence of liver disease, bowel disease, diarrhea and catabolism (unintended recent weight loss) -Heavy exercise like long-distance running one week prior to the study day -The use of RNA rich nutritional supplements (such as yeast) within a period of one month prior to the start of the study -Unable to adhere to protocol instructions -Alcohol or drug abuse in the opinion of the investigator -Investigator's uncertainty about the willingness or ability of the subject to comply with the protocol requirements -Participation in any other studies involving investigational or marketed products concomitantly or within two weeks prior to entry into the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in blood plasma levels of uridine over time, following single intake of study product. | — |
Secondary
| Measure | Time frame |
|---|---|
| N.a. | — |
Countries
Netherlands
Outcome results
None listed