atopic eczema
Conditions
Interventions
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age 18 years or older. Mild to moderate atopic dermatitis, with a SCORAD score between 15 and 40. Informed consent
Exclusion criteria
Exclusion criteria: -Oral use of prescribed vitamin D or calcium supplements. -Pregnancy -Lactating women -Patients who receive specialized treatment for disorders in calcium homeostasis and/or liver and kidney diseases. -Inflammatory skin diseases unrelated to atopic dermatitis, except acneiform eruption. -Sunny holiday during the previous 6 weeks -Use of sunbeds or UV-therapy. -Allergy/intolerance for ingredients used in the study medications. -Previously documented non-compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main endpoint will be the number of, and time to, exacerbation of atopic dermatitis. To assess a profile of which patients are better to treatable with topical vitamin D, filaggrin mutation and vitamin D levels at the start of treatment will be assessed. | — |
Secondary
| Measure | Time frame |
|---|---|
| The quality of life in patients using the different treatment and the difference of transepidermal water loss between the two treatment groups. | — |
Countries
Netherlands
Outcome results
None listed