The relationship between depressive symptoms and pro-inflammatory cytokine serum levels in adults with congenital heart disease

The relationship between depressive symptoms and pro-inflammatory cytokine serum levels in adults with congenital heart disease - Depression and cytokine serum levels

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35960

Enrollment

150

Registered

2012-02-01

Start date

2011-04-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital heart disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients - are 18 years or older - have a congenital heart defect (excluding patients with a syndrome, such as Marfan or Noonan) - are visiting the outpatient cardiology clinic of the AMC

Exclusion criteria

Exclusion criteria: Patients are not eligible if one or more of the following criteria apply: - they are diagnosed with a syndrome (such as Marfan or Noonan) - they are mentally impaired - they are unable to independently complete a questionnaire - they are not literate in Dutch

Design outcomes

Primary

Measure	Time frame
The association between depressive symptoms and the serum levels of the pro-inflammatory cytokine TNF-* in adult CHD-patients.	—

Secondary

Measure	Time frame
The association between depressive symptoms and the serum levels of the pro-inflammatory cytokines IL-1 and IL-6 in adult CHD-patients.	—

Countries

Netherlands

Outcome results