Intracranial pressure variability in migraine; A prospective study to evaluate changes in intracranial pressure during different migraine attack phases

Intracranial pressure variability in migraine; A prospective study to evaluate changes in intracranial pressure during different migraine attack phases - Intracranial pressure variability in migraine;

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35939

Enrollment

100

Registered

2011-03-23

Start date

2011-03-28

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Headache migraine

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria; i) age between 18-60 years; ii) provided written informed consent; iii) BMI 18.5-30 kg/m2

Exclusion criteria

Exclusion criteria: Exclusion criteria; i) (history of) severe otological disease possibly influencing measurements (e.g. Morbus Menière; hearing loss); ii) patients with a pacemaker and/or deep brain stimulation.

Design outcomes

Primary

Measure	Time frame
ICP measurements - The instrument to be used in the proposed study measures DPOAEs and CM continuously. From these measurements, phase shifts of DPOAEs and CM (expressed in degrees) can be recorded. These phase shifts are correlated to a certain change in ICP, expressed in daPa/ cm H2O[37]. Clinical symptoms; - Scoring of migraine attack phase according to the IHS criteria[3]; - Presence of premonitory symptoms (yawning, irritability, food cravings, fluid retention, depression, irritation, hyperactivation, hypersensitivity, dysphasia, anorexia, nausea and vertigo); - Nature of headache symptoms (severity, character, sidedness, aggravation with physical activity); - Presence of migraine associated symptoms (nausea, vomiting, photophobia, phonophobia);	—

Measure

Time frame

ICP measurements - The instrument to be used in the proposed study measures DPOAEs and CM continuously. From these measurements, phase shifts of DPOAEs and CM (expressed in degrees) can be recorded. These phase shifts are correlated to a certain change in ICP, expressed in daPa/ cm H2O[37]. Clinical symptoms; - Scoring of migraine attack phase according to the IHS criteria[3]; - Presence of premonitory symptoms (yawning, irritability, food cravings, fluid retention, depression, irritation, hyperactivation, hypersensitivity, dysphasia, anorexia, nausea and vertigo); - Nature of headache symptoms (severity, character, sidedness, aggravation with physical activity); - Presence of migraine associated symptoms (nausea, vomiting, photophobia, phonophobia);

—

Countries

Netherlands

Outcome results