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Functional MRI of satiety, the interaction between gastric and oral stimulation and related hormones in healthy men

Functional MRI of satiety, the interaction between gastric and oral stimulation and related hormones in healthy men - Satiety in the human brain

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON35878
Enrollment
15
Registered
2011-05-20
Start date
2011-07-05
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

geen aandoening

Interventions

Subjects will undergo a MRI scan (3 times). They will consume 500ml of chocolate milk (twice oral, once only gastric load) and once 500ml of water with an thinking agent (guarum). An naso-gastric tu

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Men, right-handed, normal weight (BMI between 20-25 kg/m2), age between 18 and 35 years, the willingness to be informed about possible brain abnormalities (incidental findings with MRI)

Exclusion criteria

Exclusion criteria: Not removable metal in body, smoking, excessive alcohol use, diet, medication use (different then paracetamol), claustrophobic.

Design outcomes

Secondary

MeasureTime frame
1) Subjective ratings of the desire to eat. 2) Subjective ratings of anxiety. 3) Energy intake (kJ) from the breakfast.

Primary

MeasureTime frame
1) Brain activation associated with the satiation process. 2) Fasting serum concentrations of hormones involved in the satiation process. 3) Measures of subjective ratings of hunger and fullness.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)