Impact of carbohydrate co-ingestion on the post-prandial anabolic response of protein in young and elderly men

Impact of carbohydrate co-ingestion on the post-prandial anabolic response of protein in young and elderly men - PRO-CARB study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON35860

Enrollment

Registered

2011-08-08

Start date

2012-01-13

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spiermetabolisme nvt

Interventions

The intervention consists of a single test day during which the subjects will receive a drink containing 20 gram intrinsically labelled casein with or without 75 gram carbohydrates. In addition, con

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 24 healthy, young male subjects (18-30 y) 24 healthy, elderly male subjects (70-85 y)

Exclusion criteria

Exclusion criteria: • Diabetes • Obesity (BMI > 30 kg/m2) • All co-morbidities interacting with mobility and muscle metabolism (e.g. arthrosis, arthritis, spasticity/rigidity, all neurological disorders). • Hypertension (according to WHO criteria) • Use of anticoagulants, blood diseases, allergy for lidocain

Design outcomes

Primary

Measure	Time frame
Muscle protein synthesis rate, expressed as fractional synthetic rate (FSR).	—

Secondary

Measure	Time frame
Rate of protein digestion and absorption, whole body protein balance and microvascular perfusion and diameter.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)