Identification of alcohol abuse in adults and elderly in a Dutch hospital

Identification of alcohol abuse in adults and elderly in a Dutch hospital - I A A

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35844

Enrollment

200

Registered

2011-06-22

Start date

2011-04-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

verslaving alcohol abusis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: all patiënts > 18 year screening PPO admitted internal medicine ward permission

Exclusion criteria

Exclusion criteria: no informed consent no dutch language stay shorter than 24 hours

Design outcomes

Primary

Measure	Time frame
Measurements After acquiring oral consent, patients will be interviewed with the aid of a lifestyle questionnaire. This questionnaire contains the following 10 questions: How much social contacts do you have? Are you environmentally responsible? How often do you sport? Do you watch tv? If yes, how often and what kind of programs? Do you have a cultural activity? If yes, what kind of? Do you read the paper or books? If yes, witch one? Do you go out? If yes, what kind of activities? Do you smoke?if yes, what and how much? Do you drink alcohol? If yes, AUDIT-C screening follows. Do you use any kind of drugs?. Each question of the AUDIT-C contains 5 possible answers, scoring 0-4 points per question. The maximum score is 12. A score of >= 4 or more identifies 86% of men who report drinking above recommended levels. A score of >= 4 identifies 84% of women who report hazardous drinking[14] . To avoid selection bias official informed consent will be provided after questioning. Afterwards a blood sample will be taken from the internal medicine patients, independent of the results of the questionnaire, for laboratory screening on levels of gGT, CDT and MCV. The accuracy of these markers is affected by various factors such as non-alcoholic liver damage, use of medications or drugs, and by metabolic disorders. gGT is the most commonly used biochemical measure of drinking. Chronic alcohol use of 4 or more beverages a day for 4 to 8 weeks significantly raises levels of this blood protein. CDT values become elevated substantially earlier (1-2 weeks) in response to prolonged excessive drinking. MCV increases with excessive alcohol intake after 4 to 8 weeks. It can detect evidence of earlier drinking after a long period of abstinence. The sensitivity of this marker is too low to justify its use as a single indicator. However, it has higher specificity compared with other tests[17,18]. Evaluation of clinical records Furthermore, the medical records referr	—

Measure

Time frame

Measurements After acquiring oral consent, patients will be interviewed with the aid of a lifestyle questionnaire. This questionnaire contains the following 10 questions: How much social contacts do you have? Are you environmentally responsible? How often do you sport? Do you watch tv? If yes, how often and what kind of programs? Do you have a cultural activity? If yes, what kind of? Do you read the paper or books? If yes, witch one? Do you go out? If yes, what kind of activities? Do you smoke?if yes, what and how much? Do you drink alcohol? If yes, AUDIT-C screening follows. Do you use any kind of drugs?. Each question of the AUDIT-C contains 5 possible answers, scoring 0-4 points per question. The maximum score is 12. A score of >= 4 or more identifies 86% of men who report drinking above recommended levels. A score of >= 4 identifies 84% of women who report hazardous drinking[14] . To avoid selection bias official informed consent will be provided after questioning. Afterwards a blood sample will be taken from the internal medicine patients, independent of the results of the questionnaire, for laboratory screening on levels of gGT, CDT and MCV. The accuracy of these markers is affected by various factors such as non-alcoholic liver damage, use of medications or drugs, and by metabolic disorders. gGT is the most commonly used biochemical measure of drinking. Chronic alcohol use of 4 or more beverages a day for 4 to 8 weeks significantly raises levels of this blood protein. CDT values become elevated substantially earlier (1-2 weeks) in response to prolonged excessive drinking. MCV increases with excessive alcohol intake after 4 to 8 weeks. It can detect evidence of earlier drinking after a long period of abstinence. The sensitivity of this marker is too low to justify its use as a single indicator. However, it has higher specificity compared with other tests[17,18]. Evaluation of clinical records Furthermore, the medical records referr

—

Secondary

Measure	Time frame
none	—

Countries

Netherlands

Outcome results