Can skin autofluorescence become a risk indicator for retinal detachment ?

Can skin autofluorescence become a risk indicator for retinal detachment ? - Can skin autofluorescence become a risk indicator for retinal detachment ?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35809

Enrollment

Registered

2011-10-18

Start date

2011-11-11

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

retinal ablation or detachment

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Willingness to participate. • (Post-) vitrectomy patients, previously diagnosed with retinal detachment. • Age: >18 years.

Exclusion criteria

Exclusion criteria: • Unwillingness to participate. • Dark coloured skin (Fitzpatrick type V or VI). • Skin abnormalities on both arms that will impair the reliability of the autofluorescence measurement. • Local or general active infection or inflammatory disease. • Known renal disease, current dialysis treatment, or a history of renal transplantation.;Exclusion criteria only for the pilot study • Known diabetes mellitus. • Pre-existing cardio-vascular complications • Intra-ocular implant lens.

Design outcomes

Primary

Measure	Time frame
Primary endpoint: the relation between skin AF,vitreous body AGE levels, and plasma AGE levels.	—

Secondary

Measure	Time frame
Secondary endpoint: relation between vitreous body AGE levels and severity of retinal detachment. Other study parameters: verbally asked questions about cardiovascular history, concomitant disease and medication, and current and previous smoking habits	—

Countries

Netherlands

Outcome results