Paediatric and Adult Causes of Encephalitis and Meningitis: The PACEM study.

Paediatric and Adult Causes of Encephalitis and Meningitis: The PACEM study. - PACEM-study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35777

Enrollment

200

Registered

2011-11-14

Start date

2012-01-16

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain-infection meningo-encephalitis

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients of all ages (including premature born infants) with a clinical suspicion of meningitis or encephalitis of whom central spine fluid is obtained, are eligible for inclusion in this study.

Exclusion criteria

Exclusion criteria: - neurosurgical operation in recent past (last 3 months) - drain with connection to cerebrospinal fluid

Design outcomes

Primary

Measure	Time frame
1. Detection of viruses and other micro-organisms in CSF, blood, nasopharyngeal aspirates and feces 2. Clinical signs and symptoms as defined as: headache, fever, irritability, altered consciousness, seizures, etc in relation to cause 3. Cell count, protein and glucose level of CSF and relation with causative organism 4. Death or permanent sequellae due to meningitis/encephalitis	—

Secondary

Measure	Time frame
1. Costs, duration of hospitalization and antibiotic use due to meningitis/encephalitis	—

Countries

Netherlands

Outcome results