Detection and treatment of endobronchial (pre-)malignant lesions after treatment of early stage lung cancer in COPD patients

Detection and treatment of endobronchial (pre-)malignant lesions after treatment of early stage lung cancer in COPD patients - ProFECT trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON35775

Enrollment

890

Registered

2011-08-24

Start date

2011-07-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Screening with autofluorescence bronchoscopy and direct treatment in case of detection.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: T1N0M0 or T2aN0M0 histologically proven NSCLC with a maximum tumor diameter of 4cm, treated with either anatomical surgical resection or SBRT with curative intent within the last six months. T descriptors according to the 7th edition of the TNM classification for lung cancer. ;GOLD II-IV COPD prior to resection.10

Exclusion criteria

Exclusion criteria: Adjuvant chemo-, immune- or radiotherapy Current or recent (50 mmHg.10

Design outcomes

Primary

Measure	Time frame
Five-year cancer free survival	—

Secondary

Measure	Time frame
Overall five-year survival Quality of life Cost-effectiveness	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)