Translating biomarkers from animal models to the clinic: validating assays in healthy volunteers.

Translating biomarkers from animal models to the clinic: validating assays in healthy volunteers. - IBATH (Identified biomarkers in animals translated to human)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35748

Enrollment

Registered

2011-12-05

Start date

2012-01-20

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

"cardiac hypertrophy" "heart failure"

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 30 healthy people (15 males and 15 females) above 50 years of age. Such volunteers will be selected under the supervision of a physician-cardiologist who overall judges whether the person fulfills the general criteria for a healthy person.

Exclusion criteria

Exclusion criteria: Exclusion criteria will be a (chronic) inflammatory condition and use of anti-inflammatory drugs. In a later stage, the levels of CRP, BNP and complement system proteins will be measured to confirm the absence of an inflammatory status. In case of high values, the subject will be informed and the blood sample will be dropped out from the study.

Design outcomes

Primary

Measure	Time frame
Biomarkers of inflammation as measured in the peripheral blood.	—

Secondary

Measure	Time frame
Not applicable.	—

Countries

Netherlands

Outcome results