burns full thickness
Conditions
Interventions
Two equal wound areas of at least 1% of every patient are treated, one wound
area is treated with PRP and one wound area with only standard treatment.
Sponsors
Rode Kruis Ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Adult men and women aged 18 years and older (no upper age limit) 2. A full thickness burn which needs primary or secondary transplantation 3. provision of informed consent by patient
Exclusion criteria
Exclusion criteria: 1.Likely problems, in the judgement of the investigators, with maintaining follow-up (e.g.patients with no fixed adress will be excluded) 2. Insufficient comprehension of the Dutch language to understand a rehabilitation program and other treatment information in the judgement of the attending physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint is the effect of PRP on the time in days to complete healing of the grafted butn wound sites. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Infection rate of the transplanted burn wounds in comparison with standard treatment. 2. Pain meassured daily with a VAS scale to complete healing of the paired grafted burn wound sites. 3. Scar assessment with the POSAS scale in comparsion with standard treatment after 3, 6 months and one year. | — |
Countries
Netherlands
Outcome results
None listed