FindTrial
Sign In

Metabolic adverse events before and after glucocorticoid pulse therapy in rheumatoid arthritis

Metabolic adverse events before and after glucocorticoid pulse therapy in rheumatoid arthritis - Risks of glucocorticoid pulse therapy in rheumatoid arthritis

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON35669
Enrollment
15
Registered
2010-03-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatic disease rheumatoid arthritis

Interventions

None listed

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Rheumatoid arthritis exacerbation, defined by Disease Activity Score of 5.1 or higher.

Exclusion criteria

Exclusion criteria: Patients with diabetes Patients with clinical contra-indication for pulse therapy Patients with DMARD changes during the last month

Design outcomes

Primary

MeasureTime frame
Metabolic disturbances -Physical examination: weight, blood pressure -Laboratory examination: fasting lab with a.o. an OGTT and lipid profile—

Secondary

MeasureTime frame
Disease activity -Interview: oVisual Analogue Scale (VAS)-pain, VAS-well being -Physical examination: oTender joint score oSwollen joint score -Laboratory examination: oFasting with a.o. ESR and hemoglobin Cardiovascular risk factors -Interview: Smoking, alcohol use, diabetes (family history), lipid disorder, hypertension, cardiovascular disease (family history, events), sports/activities (with questionnaire Short QUestionnaire to ASses Health enhancing physical activity). -Physical examination: Waist- en hip circumference, ankle-arm index with Doppler machine.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)