perioperatieve monitoring monitoring during anesthesia
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: -18-65 years old -right-handed -normal or corrected to normal vision -normal or corrected to normal hearing
Exclusion criteria
Exclusion criteria: -neurological impairment -motor disabilities -known allergies to Rocuronium and/or Sugammadex -regular drug intake
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the classification rate of our algorithm, i.e. the percentage of movement trials that are correctly classified as movement trials and the percentage of non-movement trials that are correctly classified as non-movement trials. Although the algorithm is programmed in such a way that it can take into account any feature from the EEG that distinguishes between the two classes, we expect the main useful feature to be the combined Event-Related Desynchronization (ERD), a power decrease in the alpha- and beta-frequency bands known to occur during (planning) of movement and Event-Related Synchronization (ERS), a power increase in approximately the same frequencies, known to occur after movement has stopped. These features have been well established in the literature and these findings have been replicated in our own lab. | — |
Secondary
| Measure | Time frame |
|---|---|
| As both EEG and EMG will be measured throughout the experiment, insight might be gained into the general influence of Rocuronium on the brain signal, muscle output and the interplay between them. | — |
Countries
Netherlands
Outcome results
None listed