A Randomised Trial comparing Surveillance with Radio-Frequency Ablation of Barrett*s Esophagus with Low-Grade Dysplasia; the SURF-study

A Randomised Trial comparing Surveillance with Radio-Frequency Ablation of Barrett*s Esophagus with Low-Grade Dysplasia; the SURF-study - Radiofrequency ablation vs surveillance

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON35588

Enrollment

120

Registered

2006-10-13

Start date

2007-06-18

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Barrett's esophagus precancerious condition

Interventions

Patients, who are randomized for radiofrequency ablation will be treated for low-grade dysplasia in Barrett's esophagus with radiofrequency ablation.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Low-grade dysplasia in Barrett's slokdarm

Exclusion criteria

Exclusion criteria: Patients with a Barrett's segment of >12cm

Design outcomes

Primary

Measure	Time frame
Rate of high-grade dysplasia and early cancer during two year follow-up	—

Secondary

Measure	Time frame
1. Rate of total histological eradication of LGD 2. Rate of total endoscopic eradication of Barretts mucosa 3. Rate of total histological eradication of Barretts mucosa 4. Number of procedures and costs 5. Acute and late complications of RFA 6. Percentage of surface regression of Barrett*s epithelium	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)