Barrett Barrett's oesophagus
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: -Barrett*s oesophagus patients with Barrett segment > 1cm -Age >18 years -Proton pump inhibitors (PPI) use longer than 4 weeks -Written informed consent
Exclusion criteria
Exclusion criteria: -Previous invasive treatment of Barrett oesophagus, e.g. endoscopic resection, radiofrequency ablation. -Presence of dysplasia -Surgery of the GI tract other than appendectomy or cholecystectomy -Motility disorders of the GI tract leading to delayed gastric emptying or altered intestinal motility -Inability to stop the use of medication influencing GI motility for 3 weeks -Inability to stop the use of proton pump inhibitors for 3 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oesophageal permeability. | — |
Secondary
| Measure | Time frame |
|---|---|
| Tissue impedance spectrum of the oesophageal epithelium. Sensitivity to oesophageal acid perfusion. | — |
Countries
Netherlands