atherosclerosis coronary artery disease
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Male athletes aged 45 years or older age, asymptomatic for heart disease who undergo exercise testing as part of a sports medical evaluation, who are able to understand the study procedure and objectives
Exclusion criteria
Exclusion criteria: Known cardiovascular disease Rhythm other than sinusrhythm Pacemaker rhythm Not able to hold breath for 25 sec. Asthma/COPD and resting heart rate > 70/min after intravenous administration with beta blocker) Iodine-allergy Hypertension (Blood pressure > 200/110 mmHg) Obesity BMI >40 kg/m2 Decreased renal function (GFR
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Risk of CV events determined with SCORE. - MDCT-cardiac imaging data: calcium score (Agatston, volume, mass), presence and severity of coronary artery disease, Total coronary atherosclerotic burden. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Life time physical activity - Incidental findings on MDCT scanning - Safety (in particular radiation exposure) and tolerability of MDCT scanning. | — |
Countries
Netherlands