overactive bladder syndrome urgency
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patient arm: patients older than 18 years with OAB diagnosed by their urologist using the criteria of more than 8 micturitions on three consecutive days of these three days they keep a micturation diary with a VAS score for urge sensation. Patients should have at least one episode of urge: sudden compelling desire to void which can not be postponed. Volunteers arm: volunteers older than 18 years are considered eligible if they have no urologic history or urinary complaints.
Exclusion criteria
Exclusion criteria: Patient arm: congestive heart disease or history of heart failure; patients on anticholinergic medication that are not willing to stop this medication; presence of post void residual urine > 100cc determined by ultrasound; presence of urinary tract infection, determined by urine sticks. Patients with urinary tract infection will be treated by antibiotics. After resolution of the infection, the patient can re-enter the study if the urine is sterile at that moment. Volunteer arm: urinary complaints or urologic history; congestive heart disease or history of hear failure; presence of postvoid residual urine > 100cc determined by ultrasound; presence of urinary tract infection, determined by urine sticks. Volunteers that present with urinary tract infection will be definitively excluded from participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| · To study the effect of position on bladder sensation in volunteers and patients with overactive bladder syndrome · To study the effect of position on voided volumes in volunteers and patients with overactive bladder syndrome · To study the relationship between bladder sensation and the voided volumes in both volunteers and patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary objectives · To characterise self consciousness in patients with OAB · To characterise the difference between volunteers and patients with OAB in regards to self consciousness and bladder perceptions · To characterise the difference between men and women in regards to self consciousness and bladder perceptions. · To determine the relationship between self-consciousness and bladder perceptions in patients with OAB · To determine the relationship between the functional bladder capacity and OAB symptoms in relation to patient perception · To relate voided volumes to patient perception. · To study the link between OAB symptoms and patient bother from OAB to self consciousness and bladder perception · To study the relationship between the functional and maximal bladder capacity in relation to OAB symptoms and bother in OAB patients. | — |
Countries
Netherlands