Sleep State Misperception Mispercieved?

Sleep State Misperception Mispercieved? - Sleep State Misperception Mispercieved?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35484

Enrollment

Registered

2009-03-26

Start date

2009-03-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paradoxical insomnia Sleep state misperception

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Diagnosis of primary insomnia 20-70 years old informed consent

Exclusion criteria

Exclusion criteria: psychotropic medication (exclusion if not at least 4 weeks off medication) metal in body severe claustrophobia major somatic disorder psychiatric disorder

Design outcomes

Primary

Measure	Time frame
This project will apply analysis tools for ERP, functional connectivity for resting state EEG, resting state fMRI and task-related fMRI, single and double pulse TMS (no repetitive TMS). Main study parameter is the pattern of neural synchronization as measured using EEG (sleep & wake)	—

Secondary

Measure	Time frame
In addition we will determine -patterns of power spectra topography as measured using EEG (sleep & wake). -Subjective to objective sleep duration discrepancy as measured using sleep logs, actigraphy and EEG. -ERP latency and amplitude (topography). -Blood oxygenation level dependent (BOLD) response in SSM versus PI versus controls during oddball task and resting state; regression of BOLD response on latency and amplitude of ERP. -Resting state functional connectivity in SSM versus PI versus controls -Structural abnormalities in SSM versus PI versus controls, using voxel-based morphometry (VBM) to measure regional volumetry and diffusion tensor imaging (DTI) to measure structural connectivity -Cortical excitability as assessed using TMS.	—

Measure

Time frame

In addition we will determine -patterns of power spectra topography as measured using EEG (sleep & wake). -Subjective to objective sleep duration discrepancy as measured using sleep logs, actigraphy and EEG. -ERP latency and amplitude (topography). -Blood oxygenation level dependent (BOLD) response in SSM versus PI versus controls during oddball task and resting state; regression of BOLD response on latency and amplitude of ERP. -Resting state functional connectivity in SSM versus PI versus controls -Structural abnormalities in SSM versus PI versus controls, using voxel-based morphometry (VBM) to measure regional volumetry and diffusion tensor imaging (DTI) to measure structural connectivity -Cortical excitability as assessed using TMS.

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Countries

Netherlands

Outcome results