cerebral dysfunction hiv-associated neurocognitive disorder
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: - diagnosis hiv - 18 years or older - capable of speaking and reading Dutch - adequate sight and hearing ability to join the study;Inclusion criteria controlgroup Diabetes mellitus: - diagnosis DM 2 - 18 years or older - capable of speaking and reading Dutch - adequate sight and hearing ability to join the study - GFR>30;Inclusion criteria controlgroup healthy volunteer: - 18 years or older - capable of speaking and reading Dutch - adequate sight and hearing ability to join the study
Exclusion criteria
Exclusion criteria: Exclusion criteria: - drugs- and/ or alcohol abuses (in the past two years) - Diagnosis of depression (current or last year) - current use of anti-depressive or anti-psychotic medication - history of learning disabilities, dyslexia or mental retardation - history of Cardiac Vascular Attack or neuro-syphilis with sustained brain damage - Vascular diseases (cerebral, cardiac and peripheral) - (pre)terminal kidney failure, defined as GFR
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Is the prevalence of a positive HAND screening test-outcome with the hiv dementia scale (less than 14 points is a positive outcome), higher in people living with hiv, compared to people living with diabetes mellitus tye 2 or healthy volunteers? | — |
Secondary
| Measure | Time frame |
|---|---|
| Can we identify determinants associated with a positive result on the hiv dementia scale? | — |
Countries
Netherlands
Outcome results
None listed