Balance disorders Balance problems
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - aged between 20 and 30 years. - aged 75 years or older, free living, ADL independent. - aged 75 years or older with a known polyneuropathy diagnosed in the past five years. - aged 75 years or older with a known visual impairment due to cataract - aged 75 years or older and not possible to stand 10 seconds in semi-tandem stance
Exclusion criteria
Exclusion criteria: - Patients unable to give a personal consent; - Walking distance 250m or less; - MMSE 23 or lower; - GDS 5 or higher; - Institutionalized; - Comorbidity: neurological disorders (stroke, M. Parkinson, dementia, muscle disease), metabolic diseases (diabetes mellitus), arthritis: rheumatoid arthritis, severe (pain and functional limitation) osteoarthritis (hip and knee), cancer: diagnosis and treatment of cancer within the last year, polymyalgia rheumatic, heart failure (NYHA 3-4), COPD (Gold 3-4), chronic pain syndrome (fibromyalgia, complex regional pain syndrome etc); - Medication: immunosuppressive drugs (e.g. prednisone, methotrexat, biologicals (TNF-alpha antagonists etc)), insulin - Hip or knee replacement; - Amputation; - Immobilization for 1 week or longer during the last 3 months; - Severe visual (visus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study parameters are the sensory weights of the proprioceptive information. The change of the sensory weights over the conditions with increasing perturbation amplitude of the proprioceptive information is a measure of sensory reweighting. The sensory reweighting can be represented by the slope of the relation proprioceptive weight and perturbation amplitude increase. Both, the proprioceptive reweighting of the left and right leg are calculated. | — |
Secondary
| Measure | Time frame |
|---|---|
| The outcomes of the tests performed in the diagnostic street of the Bronovo geriatrics Treatment Advice Center are secondary outcome measures of the present study: * Length, arm span, waist size, hip size and stand width * Muscle mass by Bio Impedance Analysis (BIA) * Hand grip strength by a hand held dynamometer * Isometric quadriceps strength * Visus, propriocepsis and vestibular function * Short Physical Performance Battery * Balance tests with closed eyes * Time up and go with and without a cognitive tasks * Walking speed during 10 meter walking test with and without cognitive task * Blood pressure after 5 minutes rest in supine position and after 1 minute and 3 minutes during stance * Cardiac output measured using a finometer | — |
Countries
Netherlands
Outcome results
None listed