The effect of oral ingestion of probiotics on the frequency and intensity of migraine attacks

The effect of oral ingestion of probiotics on the frequency and intensity of migraine attacks - Probiotics and migraine

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON35284

Enrollment

Registered

2012-01-12

Start date

2012-01-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cephalagia Headache

Interventions

One dose per day of 2 g of Ecologic® Barrier (Winclove).

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Frequency of at least 4 migraine attacks (or days) per month - Pattern of migraine attacks predictable/stable (frequency, duration, intensity) - Preferably: migraine patients with self-reported gastrointestinal complaints (before, during or after their migraine attacks), such as diarrhoea, bloating, or constipation.

Exclusion criteria

Exclusion criteria: - chronic daily migraine - medication-dependent headaches - cluster headache or tension-type headaches - antibiotics use up to two months before the start of the treatment period - probiotics use up to two weeks before the start of the treatment period - Female migraine patients who are pregnant or lactating (the migraine pattern is influenced).

Design outcomes

Secondary

Measure	Time frame
The disability due to migraine attacks is measured by validated headache questionnaires (MIDAS and HDI questionnaire).	—

Primary

Measure	Time frame
Incidence and severity of migraine attacks, measured by headache diaries	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)