autism ASD
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: General Inclusion criteria 1) Aged at least 6 years ;Inclusion criteria for subjects with ASD 1) DSM-IV (APA, 1994) diagnosis in the autism spectrum;Inclusion criteria for controls 1) no DSM-IV (APA, 1994) diagnosis 2) no scores in the clinical range on the Child Behavior Checklist (CBCL) and Teacher Rating Form (TRF) 3) IQ > 70
Exclusion criteria
Exclusion criteria: 1) major illness of the cardiovascular, the endocrine, the pulmonal or the gastrointestinal system 2) presence of metal objects in or around the body (pacemaker, dental braces) 3) history of or present neurological disorder 4) for individuals over 12 years of age: legal incompetence, defined as the obvious inability to comprehend the information that is presented by the investigator and is outlined in the Information letter and on which the decision to participate in the study is to be based
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measures will be genotype on autism risk genes and measures of brain structure, such as volume, gray and white matter density and white matter integrity. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures will be the results form questionnaires, interview and psychological assessment. | — |
Countries
Netherlands
Outcome results
None listed