cognitive deficits
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Disease free cancer patients (equal gender distribution, age-range: 18-74) treated at the NKI-AVL with chemotherapy and/or hormonal therapy will be included. Healthy partners (partner, family member or friend of the opposite sex with comparable age and education level) of patients will serve as control group to gather reference data. Patients and heatlhy controls should have sufficient proficiency in Dutch language.
Exclusion criteria
Exclusion criteria: Cancer patients: involvement of the central nervous system Healthy controls: cancer, any neurological or psychiatric symptoms which can influence cognitive performance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A subset of the participating patients (n=220) completes the following traditional neuropsychological tests: 1) Visual reaction time (FePsy); 2) WAIS III Digit Span (forward & backward); 3) Corsi Block-tapping Test; 4) Trailmaking A and B (TMT); 5) Tower of London (TOL); 6) Controlled Oral Word Association (COWA); 7) Rey Auditory Verbal Learning test, short form; 8) Grooved Pegboard; 9) Japanese and caucasian brief affect recognition test (JACBART). Also, the newly developed neuropsychological test battery is conducted by all patients (n=385) and healthy controls (n=330). This test consists of several subtests based on the here above mentioned traditional tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| - questionnaire on anxiety and depression: Hopkins Symptom Checklist-25 - demographics - short questionnaire on internet usage | — |
Countries
Netherlands