Acute effects of growth hormone on cognitive functioning and related brain physiology in healthy subjects

Acute effects of growth hormone on cognitive functioning and related brain physiology in healthy subjects - Acute effects of growth hormone

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON35220

Enrollment

Registered

2008-10-27

Start date

2009-06-30

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

veroudering Growth Hormone Deficiency (GHD) the effect of growth hormone

Interventions

One intravenous injection with either GH releasing hormone (GHRH) or placebo.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - male - age; older than 55 years old - BMI between 20 & 33

Exclusion criteria

Exclusion criteria: 1. Any history of malignant disease. 2. Any history of pituitary or hypothalamic disease. 3. Any history of other central neurological disorders, including cerebrovascular infarctions, Parkinson's disease, multiple sclerosis, Alzheimer's disease. 4. Any active or recent ( 4 U/day. 9. Use of drugs (cannabis, cocaine, amphetamines etc.). 10. Use of medication that might affect cognitive function (e.g. benzodiazepines, antidepressants, antiepileptics, etc.).

Design outcomes

Primary

Measure	Time frame
The correlation between GH and cognitive functioning, and related brain physiology in healthy subjects.	—

Secondary

Measure	Time frame
The correlation between cortisol/ testosterone and cognitive functioning, and related brain physiology in healthy subjects.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)