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Optical Tissue Stylet - descriptive observational study into paravertebral space detection in humans

Optical Tissue Stylet - descriptive observational study into paravertebral space detection in humans - OTS PS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON35212
Enrollment
12
Registered
2011-11-08
Start date
2012-01-25
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

correct needle placement

Interventions

None listed

Sponsors

Philips
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Elective unilateral thoracic surgery Age between 18 and 80 years of age Ability and willingness to provide informed consent

Exclusion criteria

Exclusion criteria: Pregnancy Photodynamic therapy Contraindications to regional anesthesia and/or allergy to amide local anesthetics. Subjects 80 years of age Severe coagulopathy Subjects with severe thoracic deformities

Design outcomes

Primary

MeasureTime frame
Main study parameters are: 1. Successfully acquired diffuse reflectance spectra obtained in the thoracic paravertebral space, and spectra obtained during needle advancement. 2. Confirmation of sonographic thoracic paravertebral localization, defined as tissue imaging in all locations of the needle where the diffuse reflectance spectra have been collected . 3. Recordings of reaction to a small test dose of lidocaine 2% with epinephrine 1:200.000 at target position for regional anesthesia (to exclude vascular localization of the needle) 4. *certainty score* on a 3-point scale (1 = uncertain, 2 = certain, 3 = very certain) provided by the physician for assignment of the type of tissue present at the needle tip, based on the information available from imaging and/or aspiration and/or reaction to a small injection of epinephrine.

Secondary

MeasureTime frame
Methylene blue will be injected after the administration of local anesthetic. Subsequently, an additional confirmation of correct needle placement within the paravertebral space will be obtained by direct visual observation of the dye in the thoracic paravertebral space by the thoracic surgeron during surgery.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)