Sugar, non-caloric sweeteners and reward

Sugar, non-caloric sweeteners and reward - SweetER

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON35205

Enrollment

Registered

2011-12-21

Start date

2012-03-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesitas obesity overweight

Interventions

sugar sweetened and non-caloric sweetened versions of a yoghurt drink and a soft drink

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Zie pag. 11 van protocol;• Age: 18-35 years • BMI: 18.5 - 25.0 kg/m2 • Healthy (as judged by the participant)

Exclusion criteria

Exclusion criteria: Zie pag. 11 van protocol • Restraint eating (men: score > 2.25; women: score > 2.80) [8] • Lack of appetite • Having difficulties with swallowing/eating • Usage of an energy restricted diet during the last two months • Weight loss or weight gain of 5 kg or more during the last two months • Stomach or bowel diseases • Diabetes, thyroid disease, other endocrine disorders • Having a history of neurological disorders • Having taste or smell disorders • Usage of daily medication other than birth control pills • For females: being pregnant or lactating • Smoking more than one cigarette a day • Being allergic/intolerant for products under study • Exclusive consumption of *light* versions of yoghurt and/or soft drinks • Working at the division of human nutrition (WUR) • Current participation in other research from the division of human nutrition (WUR) • For males: having a contra-indication to MRI scanning (see page 11 of the protocol)

Design outcomes

Primary

Measure	Time frame
The primary outcome measures of this study are 1) the shift in product preference, i.e., the difference in choice for the sugar sweetened and non-caloric sweetened yoghurt drinks and the sugar sweetened and non-caloric sweetened soft drinks (males and females) after repeated exposure and 2) the change in brain reward responses to the sugar sweetened and non-caloric sweetened drinks after repeated exposure (males).	—

Measure

Time frame

The primary outcome measures of this study are 1) the shift in product preference, i.e., the difference in choice for the sugar sweetened and non-caloric sweetened yoghurt drinks and the sugar sweetened and non-caloric sweetened soft drinks (males and females) after repeated exposure and 2) the change in brain reward responses to the sugar sweetened and non-caloric sweetened drinks after repeated exposure (males).

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Secondary

Measure	Time frame
The secondary objective of this study is to determine the effect of replacing added sugar by non-caloric sweeteners in a nutrient-rich matrix (dairy drink yoghurt) and in a nutrient-empty matrix (soft drink) after repeated consumption on: • Explicit and implicit liking and wanting of these products. • Implicit associations of these products with feelings of satiety. • Expected satiety of these products. • Ad libitum intake of these products	—

Measure

Time frame

The secondary objective of this study is to determine the effect of replacing added sugar by non-caloric sweeteners in a nutrient-rich matrix (dairy drink yoghurt) and in a nutrient-empty matrix (soft drink) after repeated consumption on: • Explicit and implicit liking and wanting of these products. • Implicit associations of these products with feelings of satiety. • Expected satiety of these products. • Ad libitum intake of these products

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)