Does physical exercise increase clotting factor VIII levels in patients with moderate or mild haemophilia A ?

Does physical exercise increase clotting factor VIII levels in patients with moderate or mild haemophilia A ? - Exercise in Haemophilia A Patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35196

Enrollment

Registered

2009-05-12

Start date

2009-08-05

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

FVIII deficiency haemophilia A

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Haemophilia A • FVIII activity 1-20%. • 18-40 years of age • Male • Normally active • Able to complete the exercise test without great difficulty

Exclusion criteria

Exclusion criteria: • History of inhibitors • No access to standard haemophilia care since birth (e.g. immigration from other country) • Joint damage which complicates riding a bicycle • A known medical condition that may deteriorate during strenuous physical activities

Design outcomes

Primary

Measure	Time frame
The primary endpoint of this study is the change in FVIII levels because of exercise in moderate and mild haemophilia A patients.	—

Secondary

Measure	Time frame
The secundary endpoints of this study are von Willebrand factor, von Willebrand propeptide and t-PA before and 10 minutes after exercise in moderate and mild haemophilia A patients.	—

Countries

Netherlands

Outcome results