Markers for gut wall integrity : a novel diagnostic and prognostic tool in adult trauma patients?

Markers for gut wall integrity : a novel diagnostic and prognostic tool in adult trauma patients? - Fabp-trauma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35184

Enrollment

600

Registered

2010-02-03

Start date

2010-03-28

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

multi-trauma patienten accidental injuries trauma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Trauma patients (every patient for which the UMCG trauma team will be summoned) 18 years of age or older

Exclusion criteria

Exclusion criteria: Age

Design outcomes

Primary

Measure	Time frame
serum I-FABP, L-FABP and urine Claudin 3	—

Secondary

Measure	Time frame
among others: age, sex, mechanism of injury, Revised Trauma Score (combining glascow coma scale, blood pressure and heart rate) upon admission, Abbreviated Injury Score/Injury Severity Score (anatomical scoring system for injury severity), EMTRA score (combining age, glascow coma scale, base excess, and prothrombin time) upon admission, SIRS score (combining temperature, heart rate, neutrophils count, respiratory rate, with a SIRS score >1 denoting the presence of SIRS), cytokine levels of TNFa, IL6, IL10	—

Measure

Time frame

among others: age, sex, mechanism of injury, Revised Trauma Score (combining glascow coma scale, blood pressure and heart rate) upon admission, Abbreviated Injury Score/Injury Severity Score (anatomical scoring system for injury severity), EMTRA score (combining age, glascow coma scale, base excess, and prothrombin time) upon admission, SIRS score (combining temperature, heart rate, neutrophils count, respiratory rate, with a SIRS score >1 denoting the presence of SIRS), cytokine levels of TNFa, IL6, IL10

—

Countries

Netherlands

Outcome results